Sang Jun Sim
Ph.D., Korea Advanced Institute of Science and Technology (KAIST)
Primary Research Area : Bioenergy, Biosensor
Office : Engineering Building, 706 (TEL) 3290-4853
E-mail : simsj@korea.ac.kr
 
Education
 
- 1988 B.S. Chemical Engineering, Seoul National University
- 1990 M.S. Chemical Engineering, Korea Advanced Institute of Science and Technology, Seoul
- 1994 Ph.D. Chemical Engineering, Korea Advanced Institute of Science and Technology, Daejeon
- 1994 - 1996 : Post doc., Biology, Massachusetts Institute of Technology (MIT)
- 1996 - 2002 : Senior Research Scientist, Korea Institute of Science and Technology (KIST), Seoul
- 1998 - 1999 : Visiting Professor, University of California, LA (UCLA)
- 2002 - 2011 : Associate Professor, Dept. of Chemical Engineering, Sungkyunkwan University, Suwon
- 2008 - 2009 : Visiting Professor, University of California, Irvine (UCI)
- 2010 - 2014 : Review Board, National Research Foundation of Korea (Division of Engineering, ICT and Convergence Research)
- 2011 - Present : Professor, Dept. of Chemical and Biological Engineering, Korea Univeristy
 
Research Area
 
- Protein Chip Development and nanobiotechnology
- Metabolic engineering for polyketide synthesis
- Photosynthesis of microalgae for carbon dioxide and hydrogen production
- Biopolymer design and engineering
- Bio-Micro Electro Mechanical Systems(MEMS)
- Biotechnology & Environment
 
Publications
 

- Cuong Cao, Xinxing Li, Jeewon Lee, Sang Jun Sim "Homogeneous Growth Gold Nanocrystals for Quantification of PSA Protien Biomarker ", Biosensors and Bioelectronics 24,1292-1297(2009)

- Nguyen,Minh Thu, Seung Phill Choi, Jinwon Lee, Jae Hwa Lee and Sang Jun Sim "Hydrothermal Acid Pretreatment of Chlamydomonas reinhardtii Biomass for Ethanol Production ", Journal of Microbiology and Biotechnology 19(2),161-166(2009)

- Xin Xing Li, Cuong Cao, Se Jong Han, Sang Jun Sim "Detection of pathogen on the catalytic growth of gold nanocrystals ", WATER RESEARCH 43,1425-1431(2009)

- Hyuk Seung Seo, Seong-Eun Kim, Kyung Yeon Han, Jin-Seung Park, Yong-Hwan Kim Sang Jun Sim,Jeewon Lee "Functional fusion mutant of Candida antarctica lipase B (CalB) expressed in Escherichia coli", BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS1794,519-525(2009)

- Je Seob Park, Sung Min Cho, Gui Young Han, Sang Jun Sim,Juhyun Park and Pil J. Yoo "Phase Controllable Transfer Printing of Patterned Polyelectrolyte Multilayers ", Langmuir 25,2575-2581(2009)

- Ji-yeon Roh,Sang Jun Sim,Jongheop Yi, Kwangsik Park, Kyu Hyuck Chung, Dong-young Ryu, and Jinhee Choi "Ecotoxicity of Silver Nanoparticles on the Soil Nematode Caenorhabditis elegans Using Functional Ecotoxicogenomics", Environmental Science&Technology 43(10)3933-3940 (2009)

- Yun Hwa Kim, Jun Pyo Kim, Se Jong Han, Sang Jun Sim "Aptamer biosensor for label-free detection of humal immunoglobulin E based on surface plasmon resonance", Sensors and Actuators B:Chemical 139,471-475(2009)

- Cuong Cao and Sang Jun Sim "Resonant Rayleigh light scattering response of individual Au nanoparticles to antigen?antibody interaction", Lab on a Chip 9,1836-1839(2009)

- Jun Pyo Kim, Byung Yang Lee, Joohyung Lee, Seunghun Hong, Sang Jun Sim "Enhancement of sensitivity and specificity by surface modification of carbon nanotubes in diagnosis of prostate cancer based on carbon nanotube field effect transistors", Biosensors and Bioelectronics 24,3372-3378(2009)

- Jae-IL PARK,Jinwon Lee,Sang Jun Sim,and Jae Hwa Lee "Production of Hydrogen from Marine Macro-algae Biomass Using Anaerobic Sewage Sludge Microflora", Biotechnology and Bioprocess Engineering 14,307.315(2009)

- Hyun Soo Jang,Kwang No Park, Jun P. Kim,Sang Jun Sim,Oh J.Kwo,Young Geun Han,Kyung Shik Lee "Sensitive DNA biosensor based on long-period grating formed on the side-polished fiber surface", OPTIC EXPRESS 17(5) 3855-3860(2009)

- Hyun Soo Jang,Kwang No Park,Chang Duk Kang, Jun Pyo Kim,Sang Jun Sim,and Kyung Shik Lee "Optical fiber SPR biosensor with sandwich assay for the detection of prostate specific antigen", Optics Communications 282,2827-2830(2009

- Cheol Hee Park, Jun Pyo Kim, Sang Wook Lee, Noo Li Jeon, Pil J. Yoo, andSang Jun Sim "A Direct, Multiplex Biosensor Platform for Pathogen Detection Based on Cross-linked Polydiacetylene (PDA)Supramolecules", advanced functional materials 19,3703-3710(2009)

- Hwa Sung Shin, Hyung Joon Kim,Sang Jun Simand Noo Li Jeon "Shear Stress Effect on Transfection of Neurons Cultured in Microfluidic Devices", Journal of Nanoscience and Nonotechnology 9,1-6(2009)

- Chang Duk Kang, Se Jong Han, Seung Phill ChoiSang Jun Sim "Fed-batch culture of astaxanthin-rich Haematococcus pluvialis by exponential nutrient feeding and stepwise light supplementation", Bioprocess And Biosystems Engineering 33,133-139(2010)

- Tam-Anh D. Nguyen , Se Jong Han , Jun Pyo Kim , Mi Sun KimSang Jun Sim "Hydrogen production of the hyperthermophilic eubacterium,Thermotoga neapolitana under N2 sparging condition", Bioresource Technology 101,S38-S41(2010

- Thao Thi-Hien Pham,Sang Jun Sim "Electrochemical analysis of gold-coated magnetic nanoparticles for detecting immunological interaction", Journal of Nanoparticle research 12,227-235(2010)

- Jeong-Yong Park, Hee Yeop Chae, Chan-Hwa Chung,Sang Jun Sim Juhyun Park, Hong H. Leea and Pil J. Yoo "Controlled wavelength reduction in surface wrinkling of poly(dimethylsiloxane)", Soft Matter6,677-684(2010)

- Seung Phill Choi, Minh Thu Nguyen,Sang Jun Sim,Sang Jun Sim "Enzymatic pretreatment of Chlamydomonas reinhardtii biomass for ethanol production ", Bioresource Technology101,5330-5336(2010)

- Zongrui Zhan, Cuong Cao, Sang Jun Sim "Quantitative detection of DNA by autocatalytic enlargement of hybridized gold nanoprobes ", Biosensors and Bioelectronics 26,511-516(2010)

- Il Kyoung Kwon, Jun Pyo Kim and Sang Jun Sim "Enhancement of sensitivity using hybrid stimulus for the diagnosis of prostate cancer based on polydiacetylene (PDA) supramolecules ", Biosensors and Bioelectronics 26,1548-1553(2010)

- Jun Pyo Kim, Il Kyung Kwon, Sang Jun Sim "The strategy of signal amplification for ultrasensitive detection of hIgE based on aptamer-modified poly(di-acetylene) supramolecules ", Biosensors and Bioelectronics 26,1548-1553(2011)

- Tien Anh Ngo, Mi-Sun Kim, Sang Jun Sim "High-yield biohydrogen production from biodiesel manufacturing waste by Thermotoga neapolitana ", International journal of hydrogen energy 36,5836-5842(2011)

- Jun Pyo Kim, Cheol Hee Park, and Sang Jun Sim "Aptamer Biosensors for Label-Free Colorimetric Detection of Human IgE Based on Polydiacetylene (PDA) Supramolecules ", Journal of Nanoscience and Nanotechnology 11,4269-4274(2011)

- Jun Pyo Kim, Seunghun Hong, and Sang Jun Sim "Apta-Biosensors for Nonlabeled Real Time Detection of Human IgE Based on Carbon Nanotube ", Journal of Nanoscience and Nanotechnology 11,4182-4187(2011

- Phuoc Long Truong,Cuong Cao, Sungho Park, Moonil Kim and Sang Jun Sim "A new method for non-labeling attomolar detection of diseases based on an individual gold nanorod immunosensor ", Lab on a Chip 11,2591-2597(2011)

- Woo sung Hwang and Sang Jun Sim "A Strategy For the Ultrasensitive Detection of Cancer Biomarkers Based on the LSPR Response of a Single AuNP", Journal of Nanoscience and Nanotechnology, Vol11, 5651-5656(2011)

- Tien anh Ngo,Mi Sun Kim and Sang Jun Sim "Thermophilic hydrogen fermentation using Termotoga neapolitana DSM 4359 by fed-batch culture. ", International journal of hydrogen energy, 36,14014-14023 (2011)

- Seung Phill Choi, Yong-Cheol Park, JungHwa Lee, Sang Jun Sim and Ho-Nam Chang "Effects of L-arginine on refolding of lysine-tagged human insulin-like growth factor 1 expressed in Escherichia coli. ", Bioprocess and Biosystems Engineering, 35, 255-263 (2012)

- Jae Jun Yoo, Seung Phill Choi, Byung Woo Kim, Sang Jun Sim "Optimal design of scalable photo-bioreactor for phototropic culturing of Haematococcus pluvialis . ", Bioprocess and Biosystems Engineering, 35, 309-315 (2012)

- Zongrui Zhan, Xingyi Ma, Cuong Cao, Sang Jun Sim. " Gold-based optical biosensor for single-mismatched DNA detection using salt-induced hybridization", Biosensors and Bioelectronics, 32, 127-132 , (2012)

- Woo sung Hwang , Phuoc Long Truong and Sang Jun Sim "Size-dependent plasmonic responses of single gold nanoparticles for analysis of biorecognition", Analytical Biochemistry, 421, 213-218 (2012)

- Il Kyoung Kwon, Min Sun Song, Sang Ho Won, Seung Phill Choi, Sang Jun Sim* "Signal amplification by magnetic force on polydiacetylene supramolecules for detection of prostate cancer ", 8, 209-213 SMALL (2012)